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MYC amplifications in myeloma cell lines: correlation with MYC-inhibitor efficacy

In multiple myeloma, elevated MYC expression is related to disease initiation and progression. We found that in myeloma cell lines, MYC gene amplifications were common and correlated with MYC mRNA and protein. In primary cell samples MYC mRNA levels were also relatively high; however gene copy numbe...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: Holien, Toril, Misund, Kristine, Olsen, Oddrun Elise, Baranowska, Katarzyna Anna, Buene, Glenn, Børset, Magne, Waage, Anders, Sundan, Anders
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673192/
https://ncbi.nlm.nih.gov/pubmed/26087190
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