Modulation of cerebral endothelial cell function by TGF-β in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition

Glioblastoma are among the most angiogenic tumors. The molecular mechanisms that control blood vessel formation by endothelial cells (EC) in glioblastoma remain incompletely understood. Transforming growth factor-β (TGF-β) is a key regulatory cytokine that has proinvasive and stemness-maintaining au...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Krishnan, Shanmugarajan, Szabo, Emese, Burghardt, Isabel, Frei, Karl, Tabatabai, Ghazaleh, Weller, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673177/
https://ncbi.nlm.nih.gov/pubmed/26090865
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