INHIBITING INVASION AND STEMNESS IN GLIOBLASTOMA BY THYMOSIN BETA 4 GENE SILENCING: A POTENTIAL THERAPEUTIC TARGET?

BACKGROUND: Glioblastoma is an incurable primary brain tumors with one of the worst 5-year survival rates among all cancers. Despite multimodal treatment involving neurosurgery, irradiation and temozolomide chemotherapy, the median overall survival is in the range of 15-16 months even in selected cl...

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Main Authors: Tabatabai, Ghazaleh, Wirsching, Hans-Georg, Krishnan, Shanmugarajan, Florea, Ana-Maria, Frei, Karl, Krayenbühl, Niklaus, Hasenbach, Kathy, Reifenberger, Guido, Weller, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144549/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.79
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