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P01.21 DIFFERENTIAL REGULATION OF TGF-β-INDUCED, ALK-5-MEDIATED VEGF RELEASE BY SMAD2/3 VERSUS SMAD1/5/8 SIGNALING IN GLIOBLASTOMA

BACKGROUND: The transforming growth factor (TGF)-β and vascular endothelial growth factor (VEGF) pathways have been attributed a major role in the pathogenesis in glioblastoma, notably immunosuppression, migration and angiogenesis, but their interactions have remained poorly understood. METHODS: We...

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Detalhes bibliográficos
Main Authors: Seystahl, K., Tritschler, I., Szabo, E., Tabatabai, G., Weller, M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185455/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.114
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