DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through notch hyper-activation

The acquisition of endocrine therapy resistance in estrogen receptor α (ERα) breast cancer patients represents a major clinical problem. Notch signalling has been extensively linked to breast cancer especially in patients who fail to respond to endocrine therapy. Following activation, Notch intracel...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Faronato, Monica, Nguyen, Van T.M., Patten, Darren K., Lombardo, Ylenia, Steel, Jennifer H., Patel, Naina, Woodley, Laura, Shousha, Sami, Pruneri, Giancarlo, Coombes, R. Charles, Magnani, Luca
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673176/
https://ncbi.nlm.nih.gov/pubmed/26093085
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