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Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species(†)

BACKGROUND: Piperlongumine (PL) is a compound isolated from the piper longum plant. It possesses anti-cancer activities through blocking the transcription factor STAT3 and by inducing reactive oxygen species (ROS) in cancer, but not normal cells. It also inhibits platelet aggregation induced by coll...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Yuan, Hengjie, Houck, Katie L., Tian, Ye, Bharadwaj, Uddalak, Hull, Ken, Zhou, Zhou, Zhou, Mingzhao, Wu, Xiaoping, Tweardy, David J., Romo, Daniel, Fu, Xiaoyun, Zhang, Yanjun, Zhang, Jianning, Dong, Jing-fei
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672935/
https://ncbi.nlm.nih.gov/pubmed/26645674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143964
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