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Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species(†)
BACKGROUND: Piperlongumine (PL) is a compound isolated from the piper longum plant. It possesses anti-cancer activities through blocking the transcription factor STAT3 and by inducing reactive oxygen species (ROS) in cancer, but not normal cells. It also inhibits platelet aggregation induced by coll...
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出版年: | PLoS One |
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主要な著者: | , , , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4672935/ https://ncbi.nlm.nih.gov/pubmed/26645674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143964 |
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