Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species(†)

BACKGROUND: Piperlongumine (PL) is a compound isolated from the piper longum plant. It possesses anti-cancer activities through blocking the transcription factor STAT3 and by inducing reactive oxygen species (ROS) in cancer, but not normal cells. It also inhibits platelet aggregation induced by coll...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Yuan, Hengjie, Houck, Katie L., Tian, Ye, Bharadwaj, Uddalak, Hull, Ken, Zhou, Zhou, Zhou, Mingzhao, Wu, Xiaoping, Tweardy, David J., Romo, Daniel, Fu, Xiaoyun, Zhang, Yanjun, Zhang, Jianning, Dong, Jing-fei
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2015
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672935/
https://ncbi.nlm.nih.gov/pubmed/26645674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143964
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