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Probing Xist RNA Structure in Cells Using Targeted Structure-Seq
The long non-coding RNA (lncRNA) Xist is a master regulator of X-chromosome inactivation in mammalian cells. Models for how Xist and other lncRNAs function depend on thermodynamically stable secondary and higher-order structures that RNAs can form in the context of a cell. Probing accessible RNA bas...
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| Veröffentlicht in: | PLoS Genet |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4672913/ https://ncbi.nlm.nih.gov/pubmed/26646615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005668 |
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