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Synergistic Antivascular and Antitumor Efficacy with Combined Cediranib and SC6889 in Intracranial Mouse Glioma

Prognosis remains extremely poor for malignant glioma. Targeted therapeutic approaches, including single agent anti-angiogenic and proteasome inhibition strategies, have not resulted in sustained anti-glioma clinical efficacy. We tested the anti-glioma efficacy of the anti-angiogenic receptor tyrosi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lobo, Merryl R., Kukino, Ayaka, Tran, Huong, Schabel, Matthias C., Springer, Charles S., Gillespie, G. Yancey, Grafe, Marjorie R., Woltjer, Randall L., Pike, Martin M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672903/
https://ncbi.nlm.nih.gov/pubmed/26645398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144488
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