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Quinacrine synergistically enhances the antivascular and antitumor efficacy of cediranib in intracranial mouse glioma
BACKGROUND: Despite malignant glioma vascularity, anti-angiogenic therapy is largely ineffective. We hypothesize that efficacy of the antiangiogenic agent cediranib is synergistically enhanced in intracranial glioma via combination with the late-stage autophagy inhibitor quinacrine. METHODS: Relativ...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3829589/ https://ncbi.nlm.nih.gov/pubmed/24092859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not119 |
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