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Rho-Associated Kinase Inhibitor (Y-27632) Attenuates Doxorubicin-Induced Apoptosis of Human Cardiac Stem Cells

BACKGROUND: Recent clinical trials using c-kit(+) human cardiac stem cells (CSCs) demonstrated promising results in increasing cardiac function and improving quality of life. However, CSC efficiency is low, likely due to limited cell survival and engraftment after transplantation. The Rho-associated...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kan, Lijuan, Smith, Aubrie, Chen, Miao, Ledford, Benjamin T., Fan, Huimin, Liu, Zhongmin, He, Jia-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672899/
https://ncbi.nlm.nih.gov/pubmed/26645568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144513
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