Rho-kinase inhibitor Y-27632 attenuates pulmonary hypertension in hyperoxia-exposed newborn rats

AIM: To test the hypothesis that neonatal hyperoxia induced pulmonary hypertension accompanied by increased Rho-kinase expression in rat lungs and that Rho-kinase inhibitor could attenuate right ventricular hypertrophy and pulmonary arterial remodeling. METHODS: Newborn rats were exposed to >95%...

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Bibliografiske detaljer
Main Authors: Chou, Hsiu-chu, Huang, Liang-ti, Yeh, Tsu-fu, Chen, Chung-ming
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002165/
https://ncbi.nlm.nih.gov/pubmed/23974518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.93
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