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Antiepileptic effects of two Rho-kinase inhibitors, Y-27632 and fasudil, in mice

BACKGROUND AND PURPOSE: Rho/Rho-kinase signalling is involved in many cellular events, including some in the CNS. However, the role of this pathway in epilepsy has not yet been assessed. Therefore, we determined the effects of two Rho-kinase inhibitors, Y-27632 and fasudil, on seizures induced by pe...

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Detalhes bibliográficos
Main Authors: İnan, S Y, Büyükafşar, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527853/
https://ncbi.nlm.nih.gov/pubmed/18536751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.225
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