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Beneficial Effects of the Rho Kinase Inhibitor Y27632 in Murine Puromycin Aminonucleoside Nephrosis

BACKGROUND AND AIMS: Rho kinase (ROCK) inhibition reduces systemic blood pressure (BP) and decreases renal damage in animal models of kidney disease. The aim of this study was to determine if ROCK inhibition might have beneficial effects in glomerular disease processes that are independent of system...

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Detalhes bibliográficos
Main Authors: Wang, Liming, Ellis, Mathew J., Fields, Timothy A., Howell, David N., Spurney, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821439/
https://ncbi.nlm.nih.gov/pubmed/18367845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000121531
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