Apoptotic Platelet Events Are Not Observed in Severe von Willebrand Disease-Type 2B Mutation p.V1316M

Thrombocytopenia and increased platelet clearance observed in von Willebrand disease-type 2B (VWD-2B) may be explained by platelet apoptosis triggered by the constitutive binding of VWF to its receptor, glycoprotein Ib (GPIb). Apoptosis was assessed in platelets from two patients with a severe VWD-2...

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Pubblicato in:PLoS One
Autori principali: Berrou, Eliane, Kauskot, Alexandre, Adam, Frédéric, Harel, Amélie, Legendre, Paulette, Lavenu Bombled, Cécile, Rothschild, Chantal, Prevost, Nicolas, Christophe, Olivier D., Lenting, Peter J., Denis, Cécile V., Rosa, Jean-Philippe, Bryckaert, Marijke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672890/
https://ncbi.nlm.nih.gov/pubmed/26645283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143896
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