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A meningococcal vaccine antigen engineered to increase thermal stability and stabilize protective epitopes

Factor H binding protein (FHbp) is part of two vaccines recently licensed for prevention of sepsis and meningitis caused by serogroup B meningococci. FHbp is classified in three phylogenic variant groups that have limited antigenic cross-reactivity, and FHbp variants in one of the groups have low th...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Konar, Monica, Pajon, Rolando, Beernink, Peter T.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672778/
https://ncbi.nlm.nih.gov/pubmed/26627237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507829112
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