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A Mutant Library Approach to Identify Improved Meningococcal Factor H Binding Protein Vaccine Antigens
Factor H binding protein (FHbp) is a virulence factor used by meningococci to evade the host complement system. FHbp elicits bactericidal antibodies in humans and is part of two recently licensed vaccines. Using human complement Factor H (FH) transgenic mice, we previously showed that binding of FH...
Zapisane w:
| Wydane w: | PLoS One |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4461315/ https://ncbi.nlm.nih.gov/pubmed/26057742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128185 |
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