Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding

BACKGROUND: Malaria is still one of the most prevalent infectious diseases in the world. Sequestration of infected erythrocytes (IEs) is the prime mediator of disease. Cytoadhesion of IEs is mediated by members of the highly diverse Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). A re...

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Vydáno v:Malar J
Hlavní autoři: Nunes-Silva, Sofia, Dechavanne, Sébastien, Moussiliou, Azizath, Pstrąg, Natalia, Semblat, Jean-Philippe, Gangnard, Stéphane, Tuikue-Ndam, Nicaise, Deloron, Philippe, Chêne, Arnaud, Gamain, Benoît
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672576/
https://ncbi.nlm.nih.gov/pubmed/26646943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-1008-5
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