Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding

BACKGROUND: Malaria is still one of the most prevalent infectious diseases in the world. Sequestration of infected erythrocytes (IEs) is the prime mediator of disease. Cytoadhesion of IEs is mediated by members of the highly diverse Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). A re...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Nunes-Silva, Sofia, Dechavanne, Sébastien, Moussiliou, Azizath, Pstrąg, Natalia, Semblat, Jean-Philippe, Gangnard, Stéphane, Tuikue-Ndam, Nicaise, Deloron, Philippe, Chêne, Arnaud, Gamain, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672576/
https://ncbi.nlm.nih.gov/pubmed/26646943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-1008-5
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