Presynaptic deletion of GIT proteins results in increased synaptic strength at a mammalian central synapse

A cytomatrix of proteins at the presynaptic active zone (CAZ) controls the strength and speed of neurotransmitter release at synapses in response to action potentials. However, the functional role of many CAZ proteins and their respective isoforms remains unresolved. Here, we demonstrate that presyn...

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Pubblicato in:Neuron
Autori principali: Montesinos, Mónica S., Dong, Wei, Goff, Kevin, Das, Brati, Guerrero-Given, Debbie, Schmalzigaug, Robert, Premont, Richard T., Satterfield, Rachel, Kamasawa, Naomi, Young, Samuel M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672385/
https://ncbi.nlm.nih.gov/pubmed/26637799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.10.042
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