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Presynaptic deletion of GIT proteins results in increased synaptic strength at a mammalian central synapse

A cytomatrix of proteins at the presynaptic active zone (CAZ) controls the strength and speed of neurotransmitter release at synapses in response to action potentials. However, the functional role of many CAZ proteins and their respective isoforms remains unresolved. Here, we demonstrate that presyn...

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Bibliographic Details
Published in:Neuron
Main Authors: Montesinos, Mónica S., Dong, Wei, Goff, Kevin, Das, Brati, Guerrero-Given, Debbie, Schmalzigaug, Robert, Premont, Richard T., Satterfield, Rachel, Kamasawa, Naomi, Young, Samuel M.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672385/
https://ncbi.nlm.nih.gov/pubmed/26637799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.10.042
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