A metastatic colon adenocarcinoma harboring BRAF V600E has a durable major response to dabrafenib/trametinib and chemotherapy

The subset of metastatic colorectal adenocarcinomas that harbor BRAF V600E mutations are aggressive tumors with significantly shortened survival and limited treatment options. Here we present a colorectal cancer patient whose disease progressed through standard chemotherapy and who developed liver m...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Williams, Casey B, McMahon, Caitlin, Ali, Siraj M, Abramovitz, Mark, Williams, Kirstin A, Klein, Jessica, McKean, Heidi, Yelensky, Roman, George, Thomas J, Elvin, Julia A, Soman, Salil, Lipson, Doron, Chmielecki, Juliann, Morosini, Deborah, Miller, Vincent A, Stephens, Philip J, Ross, Jeffrey S, Leyland-Jones, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671814/
https://ncbi.nlm.nih.gov/pubmed/26664139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S90766
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