Expression of mutant bone morphogenetic protein receptor II worsens pulmonary hypertension secondary to pulmonary fibrosis

Abstract. Pulmonary fibrosis is often complicated by pulmonary hypertension (PH), and previous studies have shown a potential link between bone morphogenetic protein receptor II (BMPR2) and PH secondary to pulmonary fibrosis. We exposed transgenic mice expressing mutant BMPR2 and control mice to rep...

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Bibliographic Details
Published in:Pulm Circ
Main Authors: Bryant, Andrew J., Robinson, Linda J., Moore, Christy S., Blackwell, Thomas R., Gladson, Santhi, Penner, Niki L., Burman, Ankita, McClellan, Lucas J., Polosukhin, Vasiliy V., Tanjore, Harikrishna, McConaha, Melinda E., Gleaves, Linda A., Talati, Megha A., Hemnes, Anna R., Fessel, Joshua P., Lawson, William E., Blackwell, Timothy S., West, James D.
Format: Artigo
Language:Inglês
Published: University of Chicago Press 2015
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671742/
https://ncbi.nlm.nih.gov/pubmed/26697175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/683811
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