Rare Variants in Transcript and Potential Regulatory Regions Explain a Small Percentage of the Missing Heritability of Complex Traits in Cattle

The proportion of genetic variation in complex traits explained by rare variants is a key question for genomic prediction, and for identifying the basis of “missing heritability”–the proportion of additive genetic variation not captured by common variants on SNP arrays. Sequence variants in transcri...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Gonzalez-Recio, Oscar, Daetwyler, Hans D., MacLeod, Iona M., Pryce, Jennie E., Bowman, Phil J., Hayes, Ben J., Goddard, Michael E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671594/
https://ncbi.nlm.nih.gov/pubmed/26642058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143945
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