Palmitate induces ER calcium depletion and apoptosis in mouse podocytes subsequent to mitochondrial oxidative stress

Pathologic alterations in podocytes lead to failure of an essential component of the glomerular filtration barrier and proteinuria in chronic kidney diseases. Elevated levels of saturated free fatty acid (FFA) are harmful to various tissues, implemented in the progression of diabetes and its complic...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Principais autores: Xu, S, Nam, S M, Kim, J-H, Das, R, Choi, S-K, Nguyen, T T, Quan, X, Choi, S J, Chung, C H, Lee, E Y, Lee, I-K, Wiederkehr, A, Wollheim, C B, Cha, S-K, Park, K-S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670935/
https://ncbi.nlm.nih.gov/pubmed/26583319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.331
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