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Peroxidase expression is decreased by palmitate in cultured podocytes but increased in podocytes of advanced diabetic nephropathy

High levels of serum free fatty acids (FFAs) are associated with lipotoxicity and type 2 diabetes. Palmitic acid (PA) is the predominant circulating saturated FFA. PA induces mitochondrial superoxide and hydrogen peroxide (H(2)O (2)) generation in cultured podocytes. To elucidate the role of PA in a...

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Bibliografiske detaljer
Udgivet i:J Cell Physiol
Main Authors: Lee, Eugene, Lee, Hyun Soon
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686159/
https://ncbi.nlm.nih.gov/pubmed/30132841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26875
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