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VEGF AND PODOCYTES IN DIABETIC NEPHROPATHY
Vascular endothelial growth factor-a (VEGF-A) is a protein secreted by podocytes that is necessary for survival of endothelial cells, podocytes and mesangial cells. VEGF-A regulates slit-diaphragm signaling and podocyte shape via VEGFR2-nephrin-nck-actin interactions. Chronic hyperglycemia-induced e...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3438453/ https://ncbi.nlm.nih.gov/pubmed/22958493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2012.06.010 |
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