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An ESI-LC-MS Method for Haptoglobin Fucosylation Analysis in Hepatocellular Carcinoma and Liver Cirrhosis

A method for detection of fucosylated glycans from haptoglobin in patient serum has been developed that provides enhanced sensitivity. The workflow involves isolation of the haptoglobin using an HPLC-based affinity column followed by glycan removal, extraction and desialylation. The fucosylated glyc...

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Bibliographic Details
Published in:J Proteome Res
Main Authors: Zhang, Yiwei, Zhu, Jianhui, Yin, Haidi, Marrero, Jorge, Zhang, Xin-Xiang, Lubman, David M.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670582/
https://ncbi.nlm.nih.gov/pubmed/26503433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.5b00792
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