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Differential Quantitative Determination of Site-Specific Intact N-Glycopeptides in Serum Haptoglobin between Hepatocellular Carcinoma and Cirrhosis Using LC-EThcD-MS/MS

Intact N-glycopeptide analysis remains challenging due to the complexity of glycopeptide structures, low abundance of glycopeptides in protein digests, and difficulties in data interpretation/quantitation. Herein, we developed a workflow that involved advanced methodologies, the EThcD- MS/MS fragmen...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Zhu, Jianhui, Chen, Zhengwei, Zhang, Jie, An, Mingrui, Wu, Jing, Yu, Qing, Skilton, St. John, Bern, Marshall, Sen, K. Ilker, Li, Lingjun, Lubman, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465142/
https://ncbi.nlm.nih.gov/pubmed/30370771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00654
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