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Negative Regulation of Peptidyl-Prolyl Isomerase Activity by Interdomain Contact in Human Pin1
Pin1 is a modular peptidyl-prolyl isomerase specific for phosphorylated Ser/Thr-Pro (pS/T-P) motifs, typically within intrinsically disordered regions (IDRs) of signaling proteins. Pin1 consists of two flexibly linked domains: an N-terminal WW domain for substrate binding and a larger C-terminal pep...
Gorde:
| Argitaratua izan da: | Structure |
|---|---|
| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4670574/ https://ncbi.nlm.nih.gov/pubmed/26602185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.08.019 |
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