Depletion of Fat Tregs Prevents Age-Associated Insulin Resistance

Age-associated insulin resistance (IR) and obesity-associated IR are two physiologically distinct forms of adult onset diabetes. While macrophage-driven inflammation is a core driver of obesity-associated IR(1–6), the underlying mechanisms of the obesity-independent yet highly prevalent age-associat...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Bapat, Sagar P., Suh, Jae Myoung, Fang, Sungsoon, Liu, Sihao, Zhang, Yang, Cheng, Albert, Zhou, Carmen, Liang, Yuqiong, LeBlanc, Mathias, Liddle, Christopher, Atkins, Annette R., Yu, Ruth T., Downes, Michael, Evans, Ronald M., Zheng, Ye
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670283/
https://ncbi.nlm.nih.gov/pubmed/26580014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16151
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