The Synergistic Local Immunosuppressive Effects of Neural Stem Cells Expressing Indoleamine 2,3-Dioxygenase (IDO) in an Experimental Autoimmune Encephalomyelitis (EAE) Animal Model

Neurodegenerative diseases provoke robust immunological reactions in the central nervous system (CNS), which further deteriorate the neural tissue damage. We hypothesized that the expression levels of indoleamine 2,3-dioxygenase (IDO), an enzyme that has potent immune suppressive activities, in neur...

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Vydáno v:PLoS One
Hlavní autoři: Lee, Young Eun, An, Jaeyeol, Lee, Kee-Hang, Kim, Sung Su, Song, Hye Jin, Pyeon, Heejang, Nam, Hyun, Kang, Kyeongjin, Joo, Kyeung Min
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670164/
https://ncbi.nlm.nih.gov/pubmed/26636969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144298
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