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Stem cells ameliorate EAE via an indoleamine 2,3-dioxygenase (IDO) mechanism
Syngeneic, pluripotent Lin(−)Sca1(+) bone marrow stem cells (SC), transferred to mice with experimental autoimmune encephalomyelitis, a model of multiple sclerosis, enhanced recovery, prevented relapses and promoted myelin repair. SC-treated mice showed elevated interferon-γ production and induction...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681256/ https://ncbi.nlm.nih.gov/pubmed/18077006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.07.025 |
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