Stem cells ameliorate EAE via an indoleamine 2,3-dioxygenase (IDO) mechanism

Syngeneic, pluripotent Lin(−)Sca1(+) bone marrow stem cells (SC), transferred to mice with experimental autoimmune encephalomyelitis, a model of multiple sclerosis, enhanced recovery, prevented relapses and promoted myelin repair. SC-treated mice showed elevated interferon-γ production and induction...

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Huvudupphovsmän: Matysiak, Mariola, Stasiołek, Mariusz, Orłowski, Wojciech, Jurewicz, Anna, Janczar, Szymon, Raine, Cedric S., Selmaj, Krzysztof
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681256/
https://ncbi.nlm.nih.gov/pubmed/18077006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.07.025
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