The Synergistic Local Immunosuppressive Effects of Neural Stem Cells Expressing Indoleamine 2,3-Dioxygenase (IDO) in an Experimental Autoimmune Encephalomyelitis (EAE) Animal Model

Neurodegenerative diseases provoke robust immunological reactions in the central nervous system (CNS), which further deteriorate the neural tissue damage. We hypothesized that the expression levels of indoleamine 2,3-dioxygenase (IDO), an enzyme that has potent immune suppressive activities, in neur...

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Udgivet i:PLoS One
Main Authors: Lee, Young Eun, An, Jaeyeol, Lee, Kee-Hang, Kim, Sung Su, Song, Hye Jin, Pyeon, Heejang, Nam, Hyun, Kang, Kyeongjin, Joo, Kyeung Min
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670164/
https://ncbi.nlm.nih.gov/pubmed/26636969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144298
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