Identification of a Novel Substance P–Neurokinin-1 Receptor MicroRNA-221-5p Inflammatory Network in Human Colonic Epithelial Cells

BACKGROUND & AIMS: Substance P (SP), a neuropeptide member of the tachykinin family, plays a critical role in colitis. MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate gene expression. We examined whether SP modulates expression of microRNAs in human colonic epithelial cells....

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Publicado en:Cell Mol Gastroenterol Hepatol
Autores principales: Fang, Kai, Sideri, Aristea, Law, Ivy Ka Man, Bakirtzi, Kyriaki, Polytarchou, Christos, Iliopoulos, Dimitrios, Pothoulakis, Charalabos
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2015
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669978/
https://ncbi.nlm.nih.gov/pubmed/26645045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2015.06.008
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