Vibrio vulnificus VvhA induces NF-κB-dependent mitochondrial cell death via lipid raft-mediated ROS production in intestinal epithelial cells

The Gram-negative bacterium Vibrio vulnificus produces hemolysin (VvhA), which induces cytotoxicity in mammalian cells. However, our understanding of the cytotoxic mechanism and the modes of action of VvhA are still fragmentary and incomplete. The recombinant protein (r) VvhA (50 pg/ml) significantl...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lee, S-J, Jung, Y H, Oh, S Y, Song, E J, Choi, S H, Han, H J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669806/
https://ncbi.nlm.nih.gov/pubmed/25695598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.19
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