Vibrio vulnificus VvhA induces NF-κB-dependent mitochondrial cell death via lipid raft-mediated ROS production in intestinal epithelial cells

The Gram-negative bacterium Vibrio vulnificus produces hemolysin (VvhA), which induces cytotoxicity in mammalian cells. However, our understanding of the cytotoxic mechanism and the modes of action of VvhA are still fragmentary and incomplete. The recombinant protein (r) VvhA (50 pg/ml) significantl...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Lee, S-J, Jung, Y H, Oh, S Y, Song, E J, Choi, S H, Han, H J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669806/
https://ncbi.nlm.nih.gov/pubmed/25695598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.19
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