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Vibrio vulnificus VvhA induces autophagy-related cell death through the lipid raft-dependent c-Src/NOX signaling pathway

VvhA, a virulent factor of Vibrio (V.) vulnificus, induces acute cell death in a destructive manner. Autophagy plays an important role in cell death, but the functional role of VvhA in autophagy-related cell death has not been elucidated yet. We found that rVvhA significantly increased LC3 puncta fo...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Song, Eun Ju, Lee, Sei-Jung, Lim, Hyeon Su, Kim, Jun Sung, Jang, Kyung Ku, Choi, Sang Ho, Han, Ho Jae
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890043/
https://ncbi.nlm.nih.gov/pubmed/27250250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27080
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