Vibrio vulnificus VvpE inhibits mucin 2 expression by hypermethylation via lipid raft-mediated ROS signaling in intestinal epithelial cells

Mucin is an important physical barrier against enteric pathogens. VvpE is an elastase encoded by Gram-negative bacterium Vibrio vulnificus; however, the functional role of VvpE in intestinal mucin (Muc) production is yet to be elucidated. The recombinant protein (r) VvpE significantly reduced the le...

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發表在:Cell Death Dis
Main Authors: Lee, S-J, Jung, Y H, Oh, S Y, Jang, K K, Lee, H S, Choi, S H, Han, H J
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2015
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669833/
https://ncbi.nlm.nih.gov/pubmed/26086960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.152
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