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Necrosis- and apoptosis-related Met cleavages have divergent functional consequences

Upon activation by its ligand hepatocyte growth factor/scatter factor, the receptor tyrosine kinase Met promotes survival, proliferation, and migration of epithelial cells during embryogenesis. Deregulated Met signaling can also promote cancer progression and metastasis. Met belongs to the functiona...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Montagne, R, Berbon, M, Doublet, L, Debreuck, N, Baranzelli, A, Drobecq, H, Leroy, C, Delhem, N, Porte, H, Copin, M-C, Dansin, E, Furlan, A, Tulasne, D
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669710/
https://ncbi.nlm.nih.gov/pubmed/25996296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.132
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