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Necrosis- and apoptosis-related Met cleavages have divergent functional consequences

Upon activation by its ligand hepatocyte growth factor/scatter factor, the receptor tyrosine kinase Met promotes survival, proliferation, and migration of epithelial cells during embryogenesis. Deregulated Met signaling can also promote cancer progression and metastasis. Met belongs to the functiona...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Montagne, R, Berbon, M, Doublet, L, Debreuck, N, Baranzelli, A, Drobecq, H, Leroy, C, Delhem, N, Porte, H, Copin, M-C, Dansin, E, Furlan, A, Tulasne, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669710/
https://ncbi.nlm.nih.gov/pubmed/25996296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.132
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