Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury

Necroptosis is a recently described Caspase 8-independent method of cell death that denotes organized cellular necrosis. The roles of RIP1 and RIP3 in mediating hepatocyte death from acute liver injury are incompletely defined. Effects of necroptosis blockade were studied by separately targeting RIP...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Deutsch, M, Graffeo, C S, Rokosh, R, Pansari, M, Ochi, A, Levie, E M, Van Heerden, E, Tippens, D M, Greco, S, Barilla, R, Tomkötter, L, Zambirinis, C P, Avanzi, N, Gulati, R, Pachter, H L, Torres-Hernandez, A, Eisenthal, A, Daley, D, Miller, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669705/
https://ncbi.nlm.nih.gov/pubmed/25950489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.126
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