TGF-β Blockade Reduces Mortality and Metabolic Changes in a Validated Murine Model of Pancreatic Cancer Cachexia

Cancer cachexia is a debilitating condition characterized by a combination of anorexia, muscle wasting, weight loss, and malnutrition. This condition affects an overwhelming majority of patients with pancreatic cancer and is a primary cause of cancer-related death. However, few, if any, effective th...

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Veröffentlicht in:PLoS One
Hauptverfasser: Greco, Stephanie H., Tomkötter, Lena, Vahle, Anne-Kristin, Rokosh, Rae, Avanzi, Antonina, Mahmood, Syed Kashif, Deutsch, Michael, Alothman, Sara, Alqunaibit, Dalia, Ochi, Atsuo, Zambirinis, Constantinos, Mohaimin, Tasnima, Rendon, Mauricio, Levie, Elliot, Pansari, Mridul, Torres-Hernandez, Alejandro, Daley, Donnele, Barilla, Rocky, Pachter, H. Leon, Tippens, Daniel, Malik, Hassan, Boutajangout, Allal, Wisniewski, Thomas, Miller, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501823/
https://ncbi.nlm.nih.gov/pubmed/26172047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132786
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