Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells

Human embryonic stem cells (hESCs) may be applied to develop human-relevant sensitive in vitro test systems for monitoring developmental toxicants. The aim of this study was to identify potential developmental toxicity mechanisms of the histone deacetylase inhibitors (HDAC) valproic acid (VPA), sube...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Meganathan, K, Jagtap, S, Srinivasan, S P, Wagh, V, Hescheler, J, Hengstler, J, Leist, M, Sachinidis, A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669700/
https://ncbi.nlm.nih.gov/pubmed/25950486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.121
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