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Synergy between docosahexaenoic acid and butyrate elicits p53-independent apoptosis via mitochondrial Ca(2+) accumulation in colonocytes
Butyrate, a short-chain fatty acid fiber fermentation product, induces colonocyte apoptosis in part via a Fas-mediated (extrinsic) pathway. In previous studies, we demonstrated that docosahexaenoic acid (DHA, 22:6(Δ4,7,10,13,16,19)) enhances the effect of butyrate by increasing mitochondrial lipid o...
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| Publicat a: | Am J Physiol Gastrointest Liver Physiol |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4669682/ https://ncbi.nlm.nih.gov/pubmed/17717041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00312.2007 |
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