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Targeted replacement of HSF1 phosphorylation sites at S303/S307 with alanine residues in mice increases cell proliferation and drug resistance

i. Mammalian heat shock factor HSF1 transcriptional activity is controlled by multitude of phosphorylations that occurs under physiological conditions or following exposure of cells to a variety of stresses. One set of HSF1 phosphorylation is on serine 303 and serine 307 (S303/S307). These HSF1 phos...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Jin, Xiongjie, Moskophidis, Demetrius, Mivechi, Nahid F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2023
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC466964/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/37540428/
https://ncbi.nlm.nih.govhttps://doi.org/10.1007/978-1-0716-3342-7_7
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