Repression of mRNA translation initiation by GIGYF1 via disrupting the eIF3-eIF4G1 interaction

Viruses can selectively repress the translation of mRNAs involved in the antiviral response. RNA viruses exploit the Grb10-interacting GYF (glycine-tyrosine-phenylalanine) proteins 2 (GIGYF2) and eukaryotic translation initiation factor 4E (eIF4E) homologous protein 4EHP to selectively repress the t...

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Bibliografske podrobnosti
izdano v:Sci Adv
Main Authors: Choi, Jung-Hyun, Luo, Jun, Hesketh, Geoffrey G., Guo, Shuyue, Pistofidis, Angelos, Ladak, Reese Jalal, An, Yuxin, Naeli, Parisa, Alain, Tommy, Schmeing, T. Martin, Gingras, Anne-Claude, Duchaine, Thomas, Zhang, Xu, Sonenberg, Nahum, Jafarnejad, Seyed Mehdi
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2024
Teme:
Biomedicine and Life Sciences
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC466957/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/39018414/
https://ncbi.nlm.nih.govhttps://doi.org/10.1126/sciadv.adl5638
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