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Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E.

Human eukaryotic translation initiation factor 4E (eIF4E) binds to the mRNA cap structure and interacts with eIF4G, which serves as a scaffold protein for the assembly of eIF4E and eIF4A to form the eIF4F complex. eIF4E is an important modulator of cell growth and proliferation. It is the least abun...

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Bibliographic Details
Main Authors: Pyronnet, S, Imataka, H, Gingras, A C, Fukunaga, R, Hunter, T, Sonenberg, N
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171121/
https://ncbi.nlm.nih.gov/pubmed/9878069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.1.270
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