Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis

BACKGROUND: Loss-of-function (LOF) mutations in the filaggrin gene (FLG) are a well-replicated risk factor for atopic dermatitis (AD) and are known to cause an epidermal barrier defect. The nature of this barrier defect is not fully understood. Patients with AD with FLG LOF mutations are known to ha...

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Xehetasun bibliografikoak
Argitaratua izan da:J Allergy Clin Immunol
Egile Nagusiak: Riethmuller, Christoph, McAleer, Maeve A., Koppes, Sjors A., Abdayem, Rawad, Franz, Jonas, Haftek, Marek, Campbell, Linda E., MacCallum, Stephanie F., McLean, W.H. Irwin, Irvine, Alan D., Kezic, Sanja
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mosby 2015
Gaiak:
Atopic Dermatitis and Skin Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669308/
https://ncbi.nlm.nih.gov/pubmed/26071937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.04.042
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