The Active Form of the Saccharomyces cerevisiae Ribonucleotide Reductase Small Subunit Is a Heterodimer in Vitro and in Vivo()

The class I ribonucleotide reductases (RNRs) are composed of two homodimeric subunits: R1 and R2. R2 houses a diferric-tyrosyl radical (Y•) cofactor. Saccharomyces cerevisiae has two R2s: Y2 (β(2)) and Y4 (β′(2)). Y4 is an unusual R2 because three residues required for iron binding have been mutated...

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發表在:Biochemistry
Main Authors: Perlstein, Deborah L., Ge, Jie, Ortigosa, Allison D., Robblee, John H., Zhang, Zhen, Huang, Mingxia, Stubbe, JoAnne
格式: Artigo
語言:Inglês
出版: 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669231/
https://ncbi.nlm.nih.gov/pubmed/16285741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051616+
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